Anna Köttgen
Principal Investigator
Institute of Genetic Epidemiology
Medical Center - University of Freiburg
Hugstetter Straße 49
79106 Freiburg
- +49 761 270-78050
- anna.koettgen@uniklinik-freiburg.de
- Homepage
Current position
Director of the Institute of Genetic Epidemiology, Medical Center - University of Freiburg
Academic training
| 2005 - 2006 | Studies of Public Health (M.P.H.), Johns Hopkins Bloomberg School of Public Health, Baltimore, USA |
| 1994 - 2001 | Studies of Human Medicine (MD), University of Freiburg |
Advanced academic qualifications
| 2011 | Habilitation, Experimental Medicine, University of Freiburg; Mentor: Dr. Gerd Walz |
| 2002 | Doctoral degree in medicine (Dr. med.), University of Freiburg |
| 2001, 2003 | United States Medical Licensing Examination Steps I and II CK |
Postgraduate positions
| Since 2021 | Speaker, CRC Initiative 1453 (Nephrogenetics) |
| Since 2019 | Program Speaker, Medical Scientist Program, Faculty of Medicine, University of Freiburg |
| Since 2017 | Director, Institute of Genetic Epidemiology, University of Freiburg |
| 2016 - 2020 | Heisenberg Professor of Genetic Epidemiology, University of Freiburg |
| Since 2016 | Co-Director, International Chronic Kidney Disease Genetics (CKDGen) Consortium |
| 2010 - 2015 | Emmy Noether Group Leader, University of Freiburg, Dept. of Medicine IV |
| Since 2009 | Professor - Adjunct, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA |
| Since 2009 | Study Site Co-Director Freiburg, German Chronic Kidney Disease Study |
| 2008 - 2009 | Assistant Scientist, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA |
| 2006 - 2008 | Postdoctoral Research Fellow, The German Research Foundation, Department of Epidemiology, Johns Hopkins University, Baltimore, USA |
Miscellaneous (Honors, Awards)
| 2021 | Member, Leopoldina National Academy of Sciences |
| 2021 | Member, The American Society for Clinical Investigation (ASCI) |
| 2020 | Co-Chair, KDIGO Controversies Conference “Genetics in CKD” |
| 2020 | State of Baden-Württemberg Award for Basic Science (Landesforschungspreis) |
| 2017 | CHARGE Consortium Golden Tiger Award for Group Leadership |
| 2017 | Franz Volhard Prize of the German Society of Nephrology |
| 2011 | Nils Alwall Prize of the German Society of Nephrology |
| 2010 | Cozzarelli Prize, National Academy of Sciences, USA |
| 2009 | Jeremiah and Rose Stamler Research Award, American Heart Association |
| 1998 - 2001 | German National Academic Foundation Scholar (Studienstiftung des deutschen Volkes) |
Publications listed in PubMed®
Publications (based on CRC1479 funding)
Scherer N, Fässler D, Borisov O, Cheng Y, Schlosser P, Wuttke M, Haug S, Li Y, Telkämper F, Patil S, Meiselbach H, Wong C, Berger U, Sekula P, Hoppmann A, Schultheiss UT, Mozaffari S, Xi Y, Graham R, Schmidts M, Köttgen M, Oefner PJ, Knauf F, Eckardt KU, Grünert SC, Estrada K, Thiele I, Hertel J, Köttgen A. Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet. 2025 Jan;57(1):193-205. doi: 10.1038/s41588-024-01965-7. Epub 2025 Jan 2.
Catalano A, Haas LS, Zodel K, Adlesic M, Cuomo F, Peighambari A, Metzger P, Huang H, Haug S, Köttgen A, Köhler N, Boerries M, Frew IJ. Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma. Kidney Int. 2024 Dec 24:S0085-2538(24)00912-8. doi: 10.1016/j.kint.2024.12.003. Epub ahead of print.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity. 2024 Nov 15:S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012. Epub ahead of print.
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