Susana Minguet
Principal Investigator
Department of Immunology, Faculty of Biology III
Signalling Research Centres BIOSS and CIBSS
University of Freiburg
Schänzlestr. 18
79104 Freiburg
- +49 761 203-67514
- susana.minguet@biologie.uni-freiburg.de
- Homepage
Current position
Academic training
| 1992 - 1997 | Study of Chemistry (Biochemistry and Molecular Biology) in Madrid, Spain |
Advanced academic qualifications
| 2018 | Habilitation in Immunology; University of Freiburg |
| 2002 | PhD in Molecular Biology, Universidad Autónoma de Madrid, Spain |
Postgraduate positions
| Since 2018 | Group Leader, Department of Immunology, University of Freiburg |
| 2011 - 2017 | Junior Group Leader, Department of Immunology, University of Freiburg |
| 2009 - 2011 | Research Fellow at CNIC, Madrid, Spain |
| 2008 - 2009 | Postdoctorate, CNIC, Madrid, Spain |
| 2002 - 2007 | Postdoctorate, MPI of Immunobiology, Freiburg |
| 1997 - 2002 | Doctorate: PhD Thesis in Molecular Biology, Universidad Autónoma de Madrid, Spain |
Miscellaneous (Honors, Awards)
| Since 2021 | Deputy Director of the ‘Spemann Graduate School of Biology and Medicine’ (SGBM), University of Freiburg |
| Since 2019 | Associated Investigator of the Excellence Cluster CIBSS, Centre for Integrative Biological Signalling Studies |
| Since 2019 | Principal Investigator and Steering Board Member of Excellent cluster BIOSS |
| 2017 | Prize to the best scientific publication from the Center of Chronic Immunodeficiencies (CCI) to the publication Minguet et al., Nature Immunology 2017 |
| 2016 - 2018 | Selected Mentee of the EIRA Mentoring program and the Freiburg Initiative for Remarkable women (FIRE) at the Medical Center University of Freiburg |
| 2016 | Baden-Württemberg Stiftung Eliteprogramm |
| 2012 | VIII Prize of Health Sciences from Fundación Caja Rural de Granada to the best original investigation to the publication Goetz, Minguet et al, Cell 2011 |
| 2009 | Research fellow awarded by the Ramón y Cajal International Program of the Spanish Ministry of Science and Innovation |
| 2003 | Prize to the best scientific publication of 2003 from Fundación Médica Mutua Madrileña |
| 1997 | PhD Fellowship from the Spanish Ministry of Science and Innovation |
Publications listed in PubMed®
Publications (based on CRC1479 funding)
Schaffer AM, Fiala GJ, Hils M, Natali E, Babrak L, Herr LA, Romero-Mulero MC, Cabezas-Wallscheid N, Rizzi M, Miho E, Schamel WWA, Minguet S. Kidins220 regulates the development of B cells bearing the λ light chain. Elife. 2024 Jan 25;13:e83943. doi: 10.7554/eLife.83943.
Velasco Cárdenas RM, Brandl SM, Meléndez AV, Schlaak AE, Buschky A, Peters T, Beier F, Serrels B, Taromi S, Raute K, Hauri S, Gstaiger M, Lassmann S, Huppa JB, Boerries M, Andrieux G, Bengsch B, Schamel WW, Minguet S. Harnessing CD3 diversity to optimize CAR T cells. Nat Immunol. 2023 Nov 6. doi: 10.1038/s41590-023-01658-z. Epub ahead of print.
Raute K, Strietz J, Parigiani MA, Andrieux G, Thomas OS, Kistner KM, Zintchenko M, Aichele P, Hofmann M, Zhou H, Weber W, Boerries M, Swamy M, Maurer J, Minguet S. Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands. Cancer Immunol Res. 2023 May 4:OF1-OF20. doi: 10.1158/2326-6066.CIR-22-0296. Epub ahead of print.
Langenbach M, Giesler S, Richtsfeld S, da Costa-Pereira S, Rindlisbacher L, Wertheimer T, Braun LM, Andrieux G, Duquesne S, Pfeifer D, Woessner NM, Menssen HD, Taromi S, Duyster J, Boerries M, Brummer T, Blazar BR, Minguet S, Turko P, Levesque MP, Becher B, Zeiser R. MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production. Mol Cancer Res. 2023 Apr 18:MCR-22-0898. doi: 10.1158/1541-7786.MCR-22-0898. Epub ahead of print.
Rückert T, Andrieux G, Boerries M, Hanke-Müller K, Woessner NM, Doetsch S, Schell C, Aumann K, Kolter J, Schmitt-Graeff A, Schiff M, Braun LM, Haring E, Kissel S, Siranosian BA, Bhatt AS, Nordkild P, Wehkamp J, Jensen BAH, Minguet S, Duyster J, Zeiser R, Köhler N. Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Sci Transl Med. 2022 Dec 21;14(676):eabp9675. doi: 10.1126/scitranslmed.abp9675. Epub 2022 Dec 21. PMID: 36542690.
free full text: https://www.science.org/stoken/author-tokens/ST-951/full
Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, Lehnertz B, Sauvageau G, Manke T, Menendez P, Walter SG, Minguet S, Laurenti E, Günther S, Grün D, Cabezas-Wallscheid N. Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells. Nat Cell Biol. 2022 Jul;24(7):1038-1048. doi: 10.1038/s41556-022-00931-x. Epub 2022 Jun 20.
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